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Gastvortrag Joke MM den Haan

Date: 29 November 2019
Summary: CD169+ macrophages in lymphoid organs: Border patrol against infections and opportunity for vaccination strategies
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Contact
Division of Virology
Department of Hygiene,
Microbiology, Social Medicine
Medical University IBK

Peter-Mayr-Straße 4b
A-6020 Innsbruck

Tel.: 0512/9003-71701
Fax: 0512/9003-73701
E-Mail: virologie@i-med.ac.at
Curriculum vitae of Prof. Dr. Dorothee von Laer
Univ.-Prof. Dr. Dorothee von Laer
Name: Prof. Dr. M. Dorothee von Laer, MD
Date of birth: 1958
Address: Division of Virology
Innsbruck Medical University
Peter-Mayr-Straße 4b
6020 Innsbruck, Austria


Education

1976-77 Interpreter School, Interpreter Diploma English
1978-85 Medical School Hamburg, Germany
1985 Final medical exam: ‘Staatsexamen’ and Approbation
1985-87 Thesis in Biochemistry
1987 Dr. med.
1994 Specialist (Facharzt) for Microbiology and Infectious Diseases
1996 Habilitation (venia legendi) at the Freiburg University


Professional Positions

Since 1/10
Full Professor for Virology and Head of the Division for Virology at the Medical University Innsbruck, Austria
2003-12/09 Full Professor for Applied Virology and Gene Therapy at the University of Frankfurt, Medical School, Germany
2000-12/09 Head of the section ‘Applied Virology and Gene Therapy’ at the Georg-Speyer-Haus, Frankfurt am Main
1996-2000 Senior scientist at the ‘Heinrich-Pette-Institut für Experimentelle Virologie’ (a biomedical research institute), Hamburg University
1992-96 Scientist at the ‘Abteilung für Virologie, Inst. f.Med. Mikrobiologie & Hygiene’ of Freiburg University, Germany
1988-91 Physician and scientist at the ‘Bernhard-Nocht-Institut für Tropenkrankheiten (tropical diseases)’, Hamburg
1987-88 Scientist at the ‘Institut für Med. Mikrobiologie’, Hamburg University


Research Projects

  • Speaker of the EU research network ’antiviral aptamers for treatment of HIV infection, Virapt’ (STREP)

  • Speaker of the BMBF consortium ‘treatment of severe immunodeficiencies with gene-modified hematopoietic stem cells, TreatID’

  • Deputy Coordinator of the Frankfurt research study group ‘Biologicals, GK1172’

  • Member of the EU Integrated Project ‘A combined pox-virus/lentiviral vector system to treat HIV infection. Immunization and direct in vivo gene transfer in T lymphocytes, Poxgene’
  • Member of the EU Integrated Project ‘targeting replication and integration of HIV, TRIOH’

  • Member of the Frankfurt integrated research network ‘RNA-ligand interaction, SFB 579’

  • Member of the French-German ANRS-funded network ‘therapy for HIV infection by "intracellular immunisation" with antiviral genes: evaluation in an SIV-infected rhesus macaque pre-clinical model’

Research profile

  • Gene therapy
  • Molecular virology
  • Oncolytic viruses

Patents approved

  • Retroviral Hybrid Vectors pseudotyped with LCMV (DE 198 56 463 ; Priority: May 1th, 1999 ; EP 99250415 ; US 6,589,763 B1)

  • Gene therapy of HIV-Infection by the expression of membrane-anchored gp41 peptides (DE 199 57 838.9, Priority: 25.11.99; PCT/EP00/11733)
  • LCMV-GP-VSV-Pseudotypvektoren und tumorinfiltrierende Virenproduzentenzellen zur Therapie von Tumoren (DE10 2008 050 860.8, Priority: 8.10.2008)

Patents submitted

  • Gene therapy of solid tumors using retroviral, with LCMV GP pseudotyped vectors (DE 10 2004 034461.2 ; Priority: 16.7.2004 ; PCT/EP2005/7687)

  • Secretable HIV entry inhibitory peptides for therapy of HIV infection (EP 08000298.3; Priority 9.1.08)